These are imperfect people, so caught up in their lives that they rarely deal with problems skillfully. Sometimes the daily outcomes are hilarious, sometimes painful. Through it all, they struggle to remember that they really are crazy about each other.
Judd Apatow probably couldn't have gotten this film made 8 years ago. His more recent successes earned him the leeway to leave the characters a little more raw, not just cute and polished. I didn't like Pete and Debbie every moment, but I never hated them... they were real and forgivable.
I'll watch this one again in a few months. I'd recommend this film to anyone, with the advisory that the language does get pretty raw in spots.
I'd advise not starting this film after 7:00 p.m., and make sure you have a pot of strong coffee, or a couple of Red Bulls, to fortify yourself as you watch.